Nanosized hydroxyapatite and β-tricalcium phosphate composite: Physico-chemical, cytotoxicity, morphological properties and in vivo trial

Physico/Chemical Characterization, In Vitro, and In Vivo Evaluation of Hydroxyapatite/PLGA Composite and Tricalcium Phosphate Particulate Grafting Materials

Background: The purpose of this study was to physico/chemically characterize and evaluate the in vitro cytotoxicity/in vivo bone regeneration of two grafting materials in a rat calvaria model. Materials and Methods: Two particulate grafting materials, Hydroxyapatite (HA)/PLGA (poly [L-lactide-co-glycolide]) composite (MA1) and Tricalcium Phosphate (MA2), were characterized by SEM, TEM, XRD (Rie...

extraction and acetylation of purified trypsin from bovin pancreas and study of some its physico-chemical properties

آنزیم تریپسین در شرایط قلیایی ناپایدار می باشد .و فعالیت پروتئولیتیکی تریپسین منجربه خود هضمی آن در جایگاههای خاصی می گردد. بنابر این آنزیمی با ناپایداری بالا محسوب میگردد. در سالهای اخیر موفق شدند که با ایجاد تغیرات شیمیایی با اضافه کردن فلزات خاص ، کلسیم و یا عمل استیلاسیون منجر به افزایش پایداری آنزیم تریپسین گردند. مطالعات در حال حاضر نشان می دهد که تریپسین استیله شده فعالیت آنزیمی خود را ...

Comparative Study of Bone Repair Using Porous Hydroxyapatite/ β-Tricalcium Phosphate and Xenograft Scaffold in Rabbits with Tibia Defect

Background: Bone tissue engineering requires materials that are biocompatible, mechanically suited for bone function, integrated with the host skeleton, and support osteoinduction of the implanted cells for new bone formation. The aim of this study was to compare the osteogenic potential of xenograft with hydroxyapatite/β- tricalcium phosphate (HA/β-TCP) scaffold. Methods: New Zealand rabbits (...

Chemical stability of grain boundaries in β-tricalcium phosphate ceramics

A New Mixture of Nano-structure of Potassium-incorporated Hydroxyapatite/β-tricalcium Phosphate/calcium Pyrophosphate

The new triphasic potassium−substituted hydroxyapatite (KHAP), β−tricalcium phosphate (β−TCP), and calcium pyrophosphate (CPP) proportions using easy sol−gel method were synthesized. The prepared powders was characterized by X–ray diffraction (XRD), Fourier transform infrared (FTIR), Differential thermal behavior (DTA) analysis, Energy Dispersive X–ray Analysis (EDXA), and Brunauer–Emmett–Telle...